Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM50396160'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50396160 (CHEMBL2171735) Show SMILES Cc1ccccc1Nc1nc2ccc(cn2n1)-c1cc(C)c(O)c(C)c1 Show InChI InChI=1S/C21H20N4O/c1-13-6-4-5-7-18(13)22-21-23-19-9-8-16(12-25(19)24-21)17-10-14(2)20(26)15(3)11-17/h4-12,26H,1-3H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of LRRK2				J Med Chem 55: 5536-45 (2012) Article DOI: 10.1021/jm300452p BindingDB Entry DOI: 10.7270/Q2RR20CQ
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50396160 (CHEMBL2171735) Show SMILES Cc1ccccc1Nc1nc2ccc(cn2n1)-c1cc(C)c(O)c(C)c1 Show InChI InChI=1S/C21H20N4O/c1-13-6-4-5-7-18(13)22-21-23-19-9-8-16(12-25(19)24-21)17-10-14(2)20(26)15(3)11-17/h4-12,26H,1-3H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Charles River Curated by ChEMBL					Assay Description Inhibition of full length wild-type LRRK2 (unknown origin) using biotinylated ezrin/radaxin/meosin peptide as substrate measured after 1 hr				Bioorg Med Chem Lett 27: 2520-2527 (2017) Article DOI: 10.1016/j.bmcl.2017.03.098 BindingDB Entry DOI: 10.7270/Q2474D0R
					More data for this Ligand-Target Pair