Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] (Homo sapiens (Human)) | BDBM551326 (8-Chloro-1-(4,4-difluoro-1-methylpyrrolidin-3-yl)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub... | Citation and Details BindingDB Entry DOI: 10.7270/Q2FN19C7 | |||||||||||
More data for this Ligand-Target Pair |