Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Leucyl-cystinyl aminopeptidase' and Ligand = 'BDBM271309'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucyl-cystinyl aminopeptidase (Rattus norvegicus)	BDBM271309 (US10059720, Example 124 | US10975091, Example 124) Show SMILES C[C@H]1CC[C@@H](CC1)Oc1ccnc(C[C@@](O)([C@@H](N)CC(C)(C)C)C(O)=O)c1 |r,wU:14.14,16.17,1.0,wD:4.7,14.15,(7.34,4.62,;6,3.85,;6,2.31,;4.67,1.54,;3.33,2.31,;3.33,3.85,;4.67,4.62,;2,1.54,;2,,;3.33,-.77,;3.33,-2.31,;2,-3.08,;.67,-2.31,;-.67,-3.08,;-2,-2.31,;-1.23,-.98,;-3.33,-3.08,;-3.33,-4.62,;-4.67,-2.31,;-6,-3.08,;-7.34,-3.85,;-6.77,-1.75,;-5.23,-4.41,;-2.77,-.98,;-2,.36,;-4.26,-1.37,;.67,-.77,)| Show InChI InChI=1S/C21H34N2O4/c1-14-5-7-16(8-6-14)27-17-9-10-23-15(11-17)12-21(26,19(24)25)18(22)13-20(2,3)4/h9-11,14,16,18,26H,5-8,12-13,22H2,1-4H3,(H,24,25)/t14-,16-,18-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.920	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent					Assay Description IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP....				US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR
					More data for this Ligand-Target Pair
Leucyl-cystinyl aminopeptidase (Rattus norvegicus)	BDBM271309 (US10059720, Example 124 | US10975091, Example 124) Show SMILES C[C@H]1CC[C@@H](CC1)Oc1ccnc(C[C@@](O)([C@@H](N)CC(C)(C)C)C(O)=O)c1 |r,wU:14.14,16.17,1.0,wD:4.7,14.15,(7.34,4.62,;6,3.85,;6,2.31,;4.67,1.54,;3.33,2.31,;3.33,3.85,;4.67,4.62,;2,1.54,;2,,;3.33,-.77,;3.33,-2.31,;2,-3.08,;.67,-2.31,;-.67,-3.08,;-2,-2.31,;-1.23,-.98,;-3.33,-3.08,;-3.33,-4.62,;-4.67,-2.31,;-6,-3.08,;-7.34,-3.85,;-6.77,-1.75,;-5.23,-4.41,;-2.77,-.98,;-2,.36,;-4.26,-1.37,;.67,-.77,)| Show InChI InChI=1S/C21H34N2O4/c1-14-5-7-16(8-6-14)27-17-9-10-23-15(11-17)12-21(26,19(24)25)18(22)13-20(2,3)4/h9-11,14,16,18,26H,5-8,12-13,22H2,1-4H3,(H,24,25)/t14-,16-,18-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.920	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent					Assay Description Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m...				US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5
					More data for this Ligand-Target Pair
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human))	BDBM271309 (US10059720, Example 124 | US10975091, Example 124) Show SMILES C[C@H]1CC[C@@H](CC1)Oc1ccnc(C[C@@](O)([C@@H](N)CC(C)(C)C)C(O)=O)c1 |r,wU:14.14,16.17,1.0,wD:4.7,14.15,(7.34,4.62,;6,3.85,;6,2.31,;4.67,1.54,;3.33,2.31,;3.33,3.85,;4.67,4.62,;2,1.54,;2,,;3.33,-.77,;3.33,-2.31,;2,-3.08,;.67,-2.31,;-.67,-3.08,;-2,-2.31,;-1.23,-.98,;-3.33,-3.08,;-3.33,-4.62,;-4.67,-2.31,;-6,-3.08,;-7.34,-3.85,;-6.77,-1.75,;-5.23,-4.41,;-2.77,-.98,;-2,.36,;-4.26,-1.37,;.67,-.77,)| Show InChI InChI=1S/C21H34N2O4/c1-14-5-7-16(8-6-14)27-17-9-10-23-15(11-17)12-21(26,19(24)25)18(22)13-20(2,3)4/h9-11,14,16,18,26H,5-8,12-13,22H2,1-4H3,(H,24,25)/t14-,16-,18-,21+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICAL CO., LTD. US Patent					Assay Description hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...				US Patent US10975091 (2021) BindingDB Entry DOI: 10.7270/Q2FF3WHR
					More data for this Ligand-Target Pair
Leucyl-cystinyl aminopeptidase (Homo sapiens (Human))	BDBM271309 (US10059720, Example 124 | US10975091, Example 124) Show SMILES C[C@H]1CC[C@@H](CC1)Oc1ccnc(C[C@@](O)([C@@H](N)CC(C)(C)C)C(O)=O)c1 |r,wU:14.14,16.17,1.0,wD:4.7,14.15,(7.34,4.62,;6,3.85,;6,2.31,;4.67,1.54,;3.33,2.31,;3.33,3.85,;4.67,4.62,;2,1.54,;2,,;3.33,-.77,;3.33,-2.31,;2,-3.08,;.67,-2.31,;-.67,-3.08,;-2,-2.31,;-1.23,-.98,;-3.33,-3.08,;-3.33,-4.62,;-4.67,-2.31,;-6,-3.08,;-7.34,-3.85,;-6.77,-1.75,;-5.23,-4.41,;-2.77,-.98,;-2,.36,;-4.26,-1.37,;.67,-.77,)| Show InChI InChI=1S/C21H34N2O4/c1-14-5-7-16(8-6-14)27-17-9-10-23-15(11-17)12-21(26,19(24)25)18(22)13-20(2,3)4/h9-11,14,16,18,26H,5-8,12-13,22H2,1-4H3,(H,24,25)/t14-,16-,18-,21+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc.; KOTOBUKI PHARMACEUTICALS CO., LTD. US Patent					Assay Description HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...				US Patent US10059720 (2018) BindingDB Entry DOI: 10.7270/Q2XD13Q5
					More data for this Ligand-Target Pair