Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene A-4 hydrolase (Homo sapiens (Human)) | BDBM50046327 (3-Amino-1,4-diphenyl-butan-2-one | CHEMBL70658) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Scripps Research Institute Curated by ChEMBL | Assay Description Ability to inhibit amidase activity of LTA4 hydrolase (1.4 ug) purified from human leukocytes | J Med Chem 36: 211-20 (1993) BindingDB Entry DOI: 10.7270/Q2T152P3 | |||||||||||
More data for this Ligand-Target Pair |