Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lipoxygenase (Glycine max (Soybean)) | BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 232 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR - Indian Institute of Chemical Biology | Assay Description The crystal structure of soybean lipoxygenase-1 (PDB code: 3PZW), was used in our docking experiments. The 3D structure of 3PZW was reported by Chrus... | Bioorg Chem 71: 97-101 (2017) Article DOI: 10.1016/j.bioorg.2017.01.016 BindingDB Entry DOI: 10.7270/Q2F76BCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lipoxygenase (Glycine max) | BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
IQOG, CSIC Curated by ChEMBL | Assay Description Inhibition of soybean lipoxygenase using sodium linoleate as substrate by UV-based analysis | J Med Chem 62: 2184-2201 (2019) Article DOI: 10.1021/acs.jmedchem.8b01987 BindingDB Entry DOI: 10.7270/Q2MC93HC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lipoxygenase (Glycine max (Soybean)) | BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 9.23E+3 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia | Assay Description The assay was progressed in 96-well microliter plates containing substrate, soybean LOX enzyme, and respective test substance at room temperature in ... | Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lipoxygenase (Glycine max) | BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 9.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Kebangsaan Malaysia Curated by ChEMBL | Assay Description Inhibition of soybean lipoxygenase after 5 mins by colorimetric assay | Bioorg Med Chem 22: 4151-61 (2014) Article DOI: 10.1016/j.bmc.2014.05.052 BindingDB Entry DOI: 10.7270/Q2GX4D6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lipoxygenase (Glycine max) | BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Zagreb Curated by ChEMBL | Assay Description Inhibition of soybean LOX using sodium linoleate as substrate by spectrophotometry | Eur J Med Chem 86: 502-14 (2014) Article DOI: 10.1016/j.ejmech.2014.09.013 BindingDB Entry DOI: 10.7270/Q2Z89F0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lipoxygenase (Glycine max) | BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbottabad University of Science and Technology Curated by ChEMBL | Assay Description Inhibition of soybean lipoxygenase | Bioorg Med Chem 26: 3731-3762 (2018) Article DOI: 10.1016/j.bmc.2018.05.042 BindingDB Entry DOI: 10.7270/Q29889HN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lipoxygenase (Glycine max) | BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of soybean LOX assessed as reduction in conversion of sodium linoleate to 13-hydroperoxylinoleic acid by UV spectroscopy | Bioorg Med Chem 22: 6586-94 (2015) Article DOI: 10.1016/j.bmc.2014.10.008 BindingDB Entry DOI: 10.7270/Q2MK6FHF | |||||||||||
More data for this Ligand-Target Pair |