Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lys-gingipain W83' and Ligand = 'BDBM453329'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lys-gingipain W83 (Porphyromonas gingivalis)	BDBM453329 (BDBM553832 | US10730826, Compound 47a) Show SMILES COC(C)(C)C(=O)NC(CCCCN)C(=O)COc1c(F)ccc(F)c1F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
CORTEXYME, INC. US Patent					Assay Description The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...				US Patent US10730826 (2020) BindingDB Entry DOI: 10.7270/Q2QR5158
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