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Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 4B' and Ligand = 'BDBM50513375'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 4B


(Homo sapiens (Human))		BDBM50513375
PNG
(CHEMBL4464471)
Show SMILES O=c1[nH]cnc2c(nccc12)-n1cc(CCN2CCC3(CC2)OCc2ccccc32)cn1
Show InChI InChI=1S/C24H24N6O2/c31-23-19-5-9-25-22(21(19)26-16-27-23)30-14-17(13-28-30)6-10-29-11-7-24(8-12-29)20-4-2-1-3-18(20)15-32-24/h1-5,9,13-14,16H,6-8,10-12,15H2,(H,26,27,31)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 57n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...

Eur J Med Chem 177: 316-337 (2019)


Article DOI: 10.1016/j.ejmech.2019.05.041
BindingDB Entry DOI: 10.7270/Q25B05TF
More data for this
Ligand-Target Pair