Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific demethylase 5A (Homo sapiens (Human)) | BDBM50324535 (3-{[9-(Dimethylamino)nonanoyl](hydroxy)amino}propa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of KDM5A (unknown origin) using H3K4me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay | J Med Chem 56: 7222-31 (2013) Article DOI: 10.1021/jm400624b BindingDB Entry DOI: 10.7270/Q2SB475V | |||||||||||
More data for this Ligand-Target Pair |