Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5B' and Ligand = 'BDBM492450'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM492450 (5-{1-[(1- fluorocyclopentyl)methyl]- 1H-pyrazol-4-...) Show SMILES CC(C)c1c([nH]c2ncnn2c1=O)-c1cnn(CC2(F)CCCC2)c1 Show InChI InChI=1S/C17H21FN6O/c1-11(2)13-14(22-16-19-10-21-24(16)15(13)25)12-7-20-23(8-12)9-17(18)5-3-4-6-17/h7-8,10-11H,3-6,9H2,1-2H3,(H,19,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.08	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...				US Patent US10975084 (2021) BindingDB Entry DOI: 10.7270/Q2K64N61
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