Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 6B' and Ligand = 'BDBM270503'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM270503 (3-[({(1R)-5-[methyl(4-methylphenyl)amino]iso-indol...) Show SMILES CN(c1ccc(C)cc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)NCc2c1 |r| Show InChI InChI=1S/C23H24N4O2/c1-15-3-5-17(6-4-15)27(2)18-7-8-19-16(11-18)12-25-22(19)14-26-21-13-24-10-9-20(21)23(28)29/h3-11,13,22,25-26H,12,14H2,1-2H3,(H,28,29)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description JMJD3: The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of t...				US Patent US11001568 (2021) BindingDB Entry DOI: 10.7270/Q22V2K7S
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM270503 (3-[({(1R)-5-[methyl(4-methylphenyl)amino]iso-indol...) Show SMILES CN(c1ccc(C)cc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)NCc2c1 |r| Show InChI InChI=1S/C23H24N4O2/c1-15-3-5-17(6-4-15)27(2)18-7-8-19-16(11-18)12-25-22(19)14-26-21-13-24-10-9-20(21)23(28)29/h3-11,13,22,25-26H,12,14H2,1-2H3,(H,28,29)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2QV3RNH
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM270503 (3-[({(1R)-5-[methyl(4-methylphenyl)amino]iso-indol...) Show SMILES CN(c1ccc(C)cc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)NCc2c1 |r| Show InChI InChI=1S/C23H24N4O2/c1-15-3-5-17(6-4-15)27(2)18-7-8-19-16(11-18)12-25-22(19)14-26-21-13-24-10-9-20(21)23(28)29/h3-11,13,22,25-26H,12,14H2,1-2H3,(H,28,29)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description JMJD3: The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of t...				US Patent US11001568 (2021) BindingDB Entry DOI: 10.7270/Q22V2K7S
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM270503 (3-[({(1R)-5-[methyl(4-methylphenyl)amino]iso-indol...) Show SMILES CN(c1ccc(C)cc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)NCc2c1 |r| Show InChI InChI=1S/C23H24N4O2/c1-15-3-5-17(6-4-15)27(2)18-7-8-19-16(11-18)12-25-22(19)14-26-21-13-24-10-9-20(21)23(28)29/h3-11,13,22,25-26H,12,14H2,1-2H3,(H,28,29)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...				US Patent US10059687 (2018) BindingDB Entry DOI: 10.7270/Q2TM7D54
					More data for this Ligand-Target Pair