Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A/REST corepressor 1' and Ligand = 'BDBM50236438'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A/REST corepressor 1 (Homo sapiens (Human))	BDBM50236438 (CHEMBL4089369) Show SMILES Cc1cc2n(C)c(cc2s1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C15H14N2OS/c1-10-8-12-14(19-10)9-13(17(12)2)15(18)16-11-6-4-3-5-7-11/h3-9H,1-2H3,(H,16,18)	PDB MMDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
European Institute of Oncology Curated by ChEMBL					Assay Description Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using biotinylated H3K4me1 peptide as substrate preincubated for 2...				J Med Chem 60: 1673-1692 (2017) Article DOI: 10.1021/acs.jmedchem.6b01018 BindingDB Entry DOI: 10.7270/Q26112KN
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