Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM256482'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM256482 (US10329256, Example 27 | US9487512, 27 | US9944601...) Show SMILES Fc1ccccc1COc1ccc(cc1)[C@H]1C[C@@H]1NCC1CCNCC1 |r| Show InChI InChI=1S/C22H27FN2O/c23-21-4-2-1-3-18(21)15-26-19-7-5-17(6-8-19)20-13-22(20)25-14-16-9-11-24-12-10-16/h1-8,16,20,22,24-25H,9-15H2/t20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute					Assay Description Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of at least eight 3-fold serial dilutions ...				Bioorg Med Chem Lett 19: 1164-7 (2009) BindingDB Entry DOI: 10.7270/Q2FX7CTX
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM256482 (US10329256, Example 27 | US9487512, 27 | US9944601...) Show SMILES Fc1ccccc1COc1ccc(cc1)[C@H]1C[C@@H]1NCC1CCNCC1 |r| Show InChI InChI=1S/C22H27FN2O/c23-21-4-2-1-3-18(21)15-26-19-7-5-17(6-8-19)20-13-22(20)25-14-16-9-11-24-12-10-16/h1-8,16,20,22,24-25H,9-15H2/t20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University					Assay Description The compounds of the invention can be tested for their ability to inhibit LSD1. The ability of the compounds of the invention to inhibit LSD1 can be ...				Bioorg Med Chem 17: 7324-36 (2009) BindingDB Entry DOI: 10.7270/Q2RF5XBG
					More data for this Ligand-Target Pair