Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM456483'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456483 (US10723742, Example 209 | US10723742, Example 213 ...) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C30H27ClF2N6O2/c1-30(2,41)14-38-28-24(36-37-38)12-21(27(33)26(28)31)19-7-5-16(29(40)39-18-6-8-25(39)23(35)11-18)9-20(19)15-3-4-17(13-34)22(32)10-15/h3-5,7,9-10,12,18,23,25,41H,6,8,11,14,35H2,1-2H3/t18-,23+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456483 (US10723742, Example 209 | US10723742, Example 213 ...) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C30H27ClF2N6O2/c1-30(2,41)14-38-28-24(36-37-38)12-21(27(33)26(28)31)19-7-5-16(29(40)39-18-6-8-25(39)23(35)11-18)9-20(19)15-3-4-17(13-34)22(32)10-15/h3-5,7,9-10,12,18,23,25,41H,6,8,11,14,35H2,1-2H3/t18-,23+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456483 (US10723742, Example 209 | US10723742, Example 213 ...) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C30H27ClF2N6O2/c1-30(2,41)14-38-28-24(36-37-38)12-21(27(33)26(28)31)19-7-5-16(29(40)39-18-6-8-25(39)23(35)11-18)9-20(19)15-3-4-17(13-34)22(32)10-15/h3-5,7,9-10,12,18,23,25,41H,6,8,11,14,35H2,1-2H3/t18-,23+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				Citation and Details BindingDB Entry DOI: 10.7270/Q2NC6513
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456483 (US10723742, Example 209 | US10723742, Example 213 ...) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C30H27ClF2N6O2/c1-30(2,41)14-38-28-24(36-37-38)12-21(27(33)26(28)31)19-7-5-16(29(40)39-18-6-8-25(39)23(35)11-18)9-20(19)15-3-4-17(13-34)22(32)10-15/h3-5,7,9-10,12,18,23,25,41H,6,8,11,14,35H2,1-2H3/t18-,23+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair