Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A [151-852]' and Ligand = 'BDBM104015'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A [151-852] (Homo sapiens (Human))	BDBM104015 (US10047086, 18 | US10640503, Example 18 | US969516...) Show SMILES N#Cc1ccc(cc1)-c1cc(OC[C@@H]2CCNC2)c2cncn2c1-c1ccc(CCN2CCOCC2)cc1 |r| Show InChI InChI=1S/C31H33N5O2/c32-18-24-3-5-26(6-4-24)28-17-30(38-21-25-9-11-33-19-25)29-20-34-22-36(29)31(28)27-7-1-23(2-8-27)10-12-35-13-15-37-16-14-35/h1-8,17,20,22,25,33H,9-16,19,21H2/t25-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay¿10 uL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM Na...				US Patent US9695168 (2017) BindingDB Entry DOI: 10.7270/Q2SX6BCD
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