Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A [151-852]' and Ligand = 'BDBM106086'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A [151-852] (Homo sapiens (Human))	BDBM106086 (US10047086, 155 | US10640503, Example 155 | US9695...) Show SMILES CC(C)n1nnc2cc(cnc12)-c1c(cc(OC[C@@H]2CCCN(C)C2)c2cncn12)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C29H30N8O/c1-19(2)37-29-25(33-34-37)11-23(14-32-29)28-24(22-8-6-20(13-30)7-9-22)12-27(26-15-31-18-36(26)28)38-17-21-5-4-10-35(3)16-21/h6-9,11-12,14-15,18-19,21H,4-5,10,16-17H2,1-3H3/t21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	7.5	25
Incyte Corporation US Patent					Assay Description LANCE LSD1/KDM1A demethylase assay¿10 uL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM Na...				US Patent US9695168 (2017) BindingDB Entry DOI: 10.7270/Q2SX6BCD
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