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Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysophosphatidylserine lipase ABHD12' and Ligand = 'BDBM50526077'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysophosphatidylserine lipase ABHD12


(Mus musculus)		BDBM50526077
PNG
(CHEMBL4578304)
Show SMILES FC(F)(F)c1ccc(nc1)N1CCC(CC1)NC(=S)Nc1cccnc1
Show InChI InChI=1S/C17H18F3N5S/c18-17(19,20)12-3-4-15(22-10-12)25-8-5-13(6-9-25)23-16(26)24-14-2-1-7-21-11-14/h1-4,7,10-11,13H,5-6,8-9H2,(H2,23,24,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.90E+3n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of JJH350 binding to ABHD12 in mouse brain membrane proteome incubated for 20 mins by CuAAC fluorescence dependent gel-based competitive A...

J Med Chem 62: 1643-1656 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01958
BindingDB Entry DOI: 10.7270/Q2377D4C
More data for this
Ligand-Target Pair