Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysosomal acid glucosylceramidase (Homo sapiens (Human)) | BDBM238209 (US9402837, 15) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.04E+4 | n/a | 4.92E+4 | n/a | n/a | n/a | n/a | 4.5 | n/a |
Amicus Therapeutics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 μ... | US Patent US9402837 (2016) BindingDB Entry DOI: 10.7270/Q2MS3RPB | |||||||||||
More data for this Ligand-Target Pair |