Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Lysosomal acid glucosylceramidase' and Ligand = 'BDBM285843'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM285843 ((6R,7R,8S)-8-(3-fluoroprop-1-yn-1-yl)-4-azaspiro[2...) Show SMILES O[C@@H]1CNC2(CC2)[C@H](C#CCF)[C@H]1O |r| Show InChI InChI=1S/C10H14FNO2/c11-5-1-2-7-9(14)8(13)6-12-10(7)3-4-10/h7-9,12-14H,3-6H2/t7-,8-,9-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	15	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
Alectos Therapeutics Inc. US Patent					Assay Description Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...				US Patent US10081601 (2018) BindingDB Entry DOI: 10.7270/Q2S184JZ
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM285843 ((6R,7R,8S)-8-(3-fluoroprop-1-yn-1-yl)-4-azaspiro[2...) Show SMILES O[C@@H]1CNC2(CC2)[C@H](C#CCF)[C@H]1O |r| Show InChI InChI=1S/C10H14FNO2/c11-5-1-2-7-9(14)8(13)6-12-10(7)3-4-10/h7-9,12-14H,3-6H2/t7-,8-,9-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alectos Therapeutics Inc. US Patent					Assay Description Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...				US Patent US9796680 (2017) BindingDB Entry DOI: 10.7270/Q2SN0C36
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM285843 ((6R,7R,8S)-8-(3-fluoroprop-1-yn-1-yl)-4-azaspiro[2...) Show SMILES O[C@@H]1CNC2(CC2)[C@H](C#CCF)[C@H]1O |r| Show InChI InChI=1S/C10H14FNO2/c11-5-1-2-7-9(14)8(13)6-12-10(7)3-4-10/h7-9,12-14H,3-6H2/t7-,8-,9-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Alectos Therapeutics Inc. US Patent					Assay Description Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...				US Patent US9796680 (2017) BindingDB Entry DOI: 10.7270/Q2SN0C36
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM285843 ((6R,7R,8S)-8-(3-fluoroprop-1-yn-1-yl)-4-azaspiro[2...) Show SMILES O[C@@H]1CNC2(CC2)[C@H](C#CCF)[C@H]1O |r| Show InChI InChI=1S/C10H14FNO2/c11-5-1-2-7-9(14)8(13)6-12-10(7)3-4-10/h7-9,12-14H,3-6H2/t7-,8-,9-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.0	n/a
Alectos Therapeutics Inc. US Patent					Assay Description Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...				US Patent US10081601 (2018) BindingDB Entry DOI: 10.7270/Q2S184JZ
					More data for this Ligand-Target Pair