BindingDB PrimarySearch

Found 23 hits Enz. Inhib. hit(s) with Target = 'Lysosomal alpha-glucosidase' and Ligand = 'BDBM50333465'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Competitive inhibition of rat alpha-glucosidase assessed as production of chromogenic p-Nitrphenol measured after 3 mins by HPLC and Michaelis-Menton...				Bioorg Med Chem Lett 21: 2441-4 (2011) Article DOI: 10.1016/j.bmcl.2011.02.062 BindingDB Entry DOI: 10.7270/Q2Z60PCK
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of Wistar rat small intestine maltase after 30 mins				Bioorg Med Chem Lett 21: 738-41 (2011) Article DOI: 10.1016/j.bmcl.2010.11.112 BindingDB Entry DOI: 10.7270/Q2D21XVS
Tohoku Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of rat intestinal maltase using moltose as substrate				J Med Chem 55: 10347-62 (2012) Article DOI: 10.1021/jm301304e BindingDB Entry DOI: 10.7270/Q2K35VTX
University of Toyama Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometry				Bioorg Med Chem Lett 24: 3298-301 (2014) Article DOI: 10.1016/j.bmcl.2014.06.001 BindingDB Entry DOI: 10.7270/Q2T43VRS
Tohoku Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of rat intestinal brush border membrane maltase				Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chulalongkorn University Curated by ChEMBL					Assay Description Inhibition of rat intestine maltase using maltose as substrate incubated for 10 mins prior to substrate addition measured after 40 mins by glucose ox...				Eur J Med Chem 66: 296-304 (2013) Article DOI: 10.1016/j.ejmech.2013.05.047 BindingDB Entry DOI: 10.7270/Q2X63PCD
Chulalongkorn University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chulalongkorn University Curated by ChEMBL					Assay Description Inhibition of rat intestinal alpha-glucosidase maltase using maltose as substrate preincubated for 10 mins prior substrate addition measured after 40...				Bioorg Med Chem Lett 22: 1538-40 (2012) Article DOI: 10.1016/j.bmcl.2012.01.007 BindingDB Entry DOI: 10.7270/Q2MK6DC7
Chulalongkorn University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kinki University Curated by ChEMBL					Assay Description Inhibition of rat small intestinal maltase after 30 mins by glucose-oxidase method				Bioorg Med Chem Lett 21: 3159-62 (2011) Article DOI: 10.1016/j.bmcl.2011.02.109 BindingDB Entry DOI: 10.7270/Q2DF6RJC
Kinki University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kinki University Curated by ChEMBL					Assay Description Inhibition of rat small intestinal maltase after 30 mins				Bioorg Med Chem 19: 2252-62 (2011) Article DOI: 10.1016/j.bmc.2011.02.028 BindingDB Entry DOI: 10.7270/Q2GH9J8R
Kinki University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kinki University Curated by ChEMBL					Assay Description Inhibition of alpha-glucosidase activity of maltase in rat small intestinal brush border membrane fraction using maltose as substrate after 30 mins				Bioorg Med Chem 20: 832-40 (2012) Article DOI: 10.1016/j.bmc.2011.11.067 BindingDB Entry DOI: 10.7270/Q20K291D
Kinki University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kinki University Curated by ChEMBL					Assay Description Inhibition of rat intestinal maltase				Bioorg Med Chem 19: 2015-22 (2011) Article DOI: 10.1016/j.bmc.2011.01.052 BindingDB Entry DOI: 10.7270/Q2J1044C
Kinki University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chulalongkorn University Curated by ChEMBL					Assay Description Inhibition of rat intestinal Maltase using maltose as substrate assessed as glucose release after 10 mins by glucose oxidase method				Bioorg Med Chem Lett 25: 4529-33 (2015) Article DOI: 10.1016/j.bmcl.2015.08.069 BindingDB Entry DOI: 10.7270/Q2WD42C3
Chulalongkorn University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of rat intestinal maltase using maltose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...				Bioorg Med Chem 21: 5442-50 (2013) Article DOI: 10.1016/j.bmc.2013.06.002 BindingDB Entry DOI: 10.7270/Q2HD7X24
Xi'an Jiaotong University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of maltase in human Caco-2 cell model system after 2 hrs				Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article	n/a	n/a	6.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat intestinal alpha-glucosidase using p-nitrophenyl- alpha-D-glucopyranoside as substrate preincubated for 5 min before addition of su...				Citation and Details Article DOI: 10.1007/s00044-010-9377-3 BindingDB Entry DOI: 10.7270/Q2S75K6S
TBA					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of maltase in rat intestinal mucosa pre-incubated for 40 mins using maltose substrate				J Nat Prod 78: 1977-89 (2015) Article DOI: 10.1021/acs.jnatprod.5b00331 BindingDB Entry DOI: 10.7270/Q23R0VN0
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article	n/a	n/a	1.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat intestinal alpha-glucosidase using para-nitrophenyl-alpha-D-glucopyranoside as substrate incubated for 5 min prior to substrate add...				Citation and Details Article DOI: 10.1007/s00044-011-9583-7 BindingDB Entry DOI: 10.7270/Q25Q501R
TBA					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of rat intestinal maltase using maltose as substrate by colorimetric analysis				Bioorg Med Chem Lett 23: 2022-6 (2013) Article DOI: 10.1016/j.bmcl.2013.02.011 BindingDB Entry DOI: 10.7270/Q2CV4K3J
Xi'an Jiaotong University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of human lysosomal alpha-glucosidase				Bioorg Med Chem 16: 7330-6 (2008) Article DOI: 10.1016/j.bmc.2008.06.026 BindingDB Entry DOI: 10.7270/Q27D2W2B
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Mus musculus (Mouse))	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
North Maharashtra University Curated by ChEMBL					Assay Description Inhibition of liver glucosidase in Swiss mouse liver extracts				Bioorg Med Chem Lett 22: 7011-4 (2012) Article DOI: 10.1016/j.bmcl.2012.10.025 BindingDB Entry DOI: 10.7270/Q2FN17CD
North Maharashtra University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.02E+5	n/a	n/a	n/a	n/a	n/a	n/a
North Maharashtra University Curated by ChEMBL					Assay Description Inhibition of pure alpha-glucosidase (unknown origin) assessed as para-nitrophenol release at 420 nm OD				Eur J Med Chem 59: 304-9 (2013) Article DOI: 10.1016/j.ejmech.2012.11.020 BindingDB Entry DOI: 10.7270/Q2028SV2
North Maharashtra University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4.47E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hebei University Curated by ChEMBL					Assay Description Inhibition of alpha-glucosidase (unknown origin) pre-incubated for 20 mins before p-nitrophenyl glycoside substrate addition				J Nat Prod 78: 1816-22 (2015) Article DOI: 10.1021/np500885f BindingDB Entry DOI: 10.7270/Q2C82C20
Hebei University Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Homo sapiens (Human))	BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) Show SMILES Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article	n/a	n/a	1.70E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of alpha-glucosidase (unknown origin) using para-nitrophenyl-alpha-D-glucopyranoside as substrate incubated for 15 min prior to substrate ...				Citation and Details Article DOI: 10.1007/s00044-012-9974-4 BindingDB Entry DOI: 10.7270/Q22B91W5
TBA					More data for this Ligand-Target Pair