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Compile Data Set for Download or QSAR
Found
4
hits Enz. Inhib. hit(s) with Target = 'Lysosomal alpha-glucosidase' and Ligand = 'BDBM50583379'
Target/Host
(Institution)
Ligand
Target/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
k
off
s
-1
k
on
M
-1
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-1
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°C
Lysosomal alpha-glucosidase
(Homo sapiens (Human))
BDBM50583379
(CHEMBL5028138 | US20230339856, Compound (IIb))
Show SMILES
CCC[C@]1(CO)NC[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI
PDB
NCI pathway
KEGG
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PC cid
PC sid
UniChem
Article
PubMed
59
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...
Citation and Details
Article DOI:
10.1021/acs.jmedchem.1c01673
BindingDB Entry DOI:
10.7270/Q23J3HVM
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase
(Homo sapiens (Human))
BDBM50583379
(CHEMBL5028138 | US20230339856, Compound (IIb))
Show SMILES
CCC[C@]1(CO)NC[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI
PDB
NCI pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
1.30E+4
n/a
n/a
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Citation and Details
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase
(Homo sapiens (Human))
BDBM50583379
(CHEMBL5028138 | US20230339856, Compound (IIb))
Show SMILES
CCC[C@]1(CO)NC[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI
PDB
NCI pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
n/a
n/a
390
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Citation and Details
More data for this
Ligand-Target Pair
Lysosomal alpha-glucosidase
(Homo sapiens (Human))
BDBM50583379
(CHEMBL5028138 | US20230339856, Compound (IIb))
Show SMILES
CCC[C@]1(CO)NC[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI
PDB
NCI pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
n/a
n/a
1.04E+5
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Citation and Details
More data for this
Ligand-Target Pair
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