Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysyl oxidase homolog 2' and Ligand = 'BDBM454359'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM454359 (US10717734, Compound 35) Show SMILES Cc1c(Cc2ccc(c(Cl)c2)S(C)(=O)=O)c2ncccc2n1C\C(F)=C\CN Show InChI InChI=1S/C20H21ClFN3O2S/c1-13-16(10-14-5-6-19(17(21)11-14)28(2,26)27)20-18(4-3-9-24-20)25(13)12-15(22)7-8-23/h3-7,9,11H,8,10,12,23H2,1-2H3/b15-7-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd. US Patent					Assay Description LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...				US Patent US10717734 (2020) BindingDB Entry DOI: 10.7270/Q25T3PHK
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