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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysyl oxidase homolog 2' and Ligand = 'BDBM454367'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysyl oxidase homolog 2


(Homo sapiens (Human))		BDBM454367
PNG
(US10717734, Compound 43)
Show SMILES CCS(=O)(=O)c1ccc(Cc2c(C(C)C)n(C\C(F)=C\CN)c3cccnc23)cn1
Show InChI InChI=1S/C22H27FN4O2S/c1-4-30(28,29)20-8-7-16(13-26-20)12-18-21-19(6-5-11-25-21)27(22(18)15(2)3)14-17(23)9-10-24/h5-9,11,13,15H,4,10,12,14,24H2,1-3H3/b17-9-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<3.00E+5n/an/an/an/an/an/a



Pharmaxis Ltd.

US Patent


Assay Description
LOX and LOXL2: Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen ...

US Patent US10717734 (2020)


BindingDB Entry DOI: 10.7270/Q25T3PHK
More data for this
Ligand-Target Pair