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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysyl oxidase homolog 2' and Ligand = 'BDBM50505661'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysyl oxidase homolog 2


(Homo sapiens (Human))		BDBM50505661
PNG
(CHEMBL4574820)
Show SMILES Cl.CN(C)C(=O)c1ccc2c(c(C)n(C\C(F)=C\CN)c2c1)-c1cccc(c1)S(=O)(=O)N(C)C
Show InChI InChI=1S/C24H29FN4O3S/c1-16-23(17-7-6-8-20(13-17)33(31,32)28(4)5)21-10-9-18(24(30)27(2)3)14-22(21)29(16)15-19(25)11-12-26/h6-11,13-14H,12,15,26H2,1-5H3/b19-11-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 63n/an/an/an/an/an/a



Pharmaxis Ltd

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...

J Med Chem 62: 9874-9889 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01283
BindingDB Entry DOI: 10.7270/Q2VM4GJ2
More data for this
Ligand-Target Pair