Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'M-phase inducer phosphatase 2' and Ligand = 'BDBM50296442'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50296442 (5-(2-methyl-3-phenylallylidene)-2-(phenylamino)thi...) Show SMILES CC(C=C1SC(Nc2cc(Cl)cc(Cl)c2)=NC1=O)=Cc1ccccc1 |w:2.1,18.20,c:15| Show InChI InChI=1S/C19H14Cl2N2OS/c1-12(7-13-5-3-2-4-6-13)8-17-18(24)23-19(25-17)22-16-10-14(20)9-15(21)11-16/h2-11H,1H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sejong University Curated by ChEMBL					Assay Description Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...				Bioorg Med Chem Lett 19: 4330-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.084 BindingDB Entry DOI: 10.7270/Q2NZ87P2
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