Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 2' and Ligand = 'BDBM348745'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM348745 (US9790235, Number I-1) Show SMILES C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)ccc5[N+]([O-])=O)ccc4c23)C(=O)N1 |r| Show InChI InChI=1S/C21H16FN5O3S/c1-10-9-23-19-18-12-3-7-17(26-14-8-11(22)2-5-15(14)27(29)30)25-13(12)4-6-16(18)31-20(19)21(28)24-10/h2-8,10,23H,9H2,1H3,(H,24,28)(H,25,26)/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene CAR LLC US Patent					Assay Description Compounds I-1 through I-50 of the invention were assayed in a mass spectrometric assay to measure their ability to covalently modify MK2 protein. The...				US Patent US9790235 (2017) BindingDB Entry DOI: 10.7270/Q2NZ89RS
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