Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 2' and Ligand = 'BDBM50045422'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50045422 (CHEMBL3314143) Show SMILES N#Cc1ccc(cc1)-c1ccc(o1)-c1nncn1-c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C23H20N6O/c24-15-17-1-3-18(4-2-17)21-9-10-22(30-21)23-27-26-16-29(23)20-7-5-19(6-8-20)28-13-11-25-12-14-28/h1-10,16,25H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 (unknown origin) incubated for 30 mins by MK2 IMAP assay				Bioorg Med Chem Lett 24: 3609-13 (2014) Article DOI: 10.1016/j.bmcl.2014.05.024 BindingDB Entry DOI: 10.7270/Q2F47QR7
					More data for this Ligand-Target Pair