Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 2' and Ligand = 'BDBM50344727'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50344727 (2'-(2-(6-aminopyridin-3-yl)pyrimidin-4-yl)-5',6'-d...) Show SMILES Nc1ccc(cn1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O Show InChI InChI=1S/C20H21N7O/c21-16-2-1-12(10-24-16)18-23-6-3-14(27-18)15-9-13-17(26-15)20(11-25-19(13)28)4-7-22-8-5-20/h1-3,6,9-10,22,26H,4-5,7-8,11H2,(H2,21,24)(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MK2 pretreated for 30 mins before fluorescein labeled substrate peptide addition measured after 2 hrs by IMAP assay				Bioorg Med Chem Lett 21: 3823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.04.016 BindingDB Entry DOI: 10.7270/Q2FT8MCB
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