Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-interacting serine/threonine-protein kinase 1/2' and Ligand = 'BDBM50520278'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1/2 (Homo sapiens (Human))	BDBM50520278 (CHEMBL4569209) Show SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cncc(c1)-c1cn[nH]c1C Show InChI InChI=1S/C19H20N4O2/c1-11(2)25-18-7-13(4-5-16(18)19(20)24)14-6-15(9-21-8-14)17-10-22-23-12(17)3/h4-11H,1-3H3,(H2,20,24)(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
A*STAR Curated by ChEMBL					Assay Description Inhibition of MNK1/MNK2 in human HeLa cells overexpressing eIF4E assessed as reduction in eIF4E phosphorylation at Ser209 residue after 2 hrs by Alph...				J Med Chem 63: 621-637 (2020) Article DOI: 10.1021/acs.jmedchem.9b01582 BindingDB Entry DOI: 10.7270/Q27084T7
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