Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-interacting serine/threonine-protein kinase 1' and Ligand = 'BDBM50277642'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (Homo sapiens (Human))	BDBM50277642 (CHEMBL4159438) Show SMILES COCCn1cc(-c2ccnc(Nc3ccc(OC)cc3OC)n2)c2ccccc12 Show InChI InChI=1S/C23H24N4O3/c1-28-13-12-27-15-18(17-6-4-5-7-21(17)27)19-10-11-24-23(25-19)26-20-9-8-16(29-2)14-22(20)30-3/h4-11,14-15H,12-13H2,1-3H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Antagonistic activity towards ET- l-induced contraction in porcine coronary arteries				Eur J Med Chem 139: 762-772 (2017) Article DOI: 10.1016/j.ejmech.2017.08.006 BindingDB Entry DOI: 10.7270/Q24B33VW
					More data for this Ligand-Target Pair