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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM238138'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Mus musculus (Mouse))
BDBM238138
PNG
(US9394289, 35)
Show SMILES CC(=O)N1CCC(O)(CC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:29|
Show InChI InChI=1S/C26H31N5O3/c1-17(32)31-12-10-26(34,11-13-31)19-4-5-22(30-24(33)23-28-16-20(15-27)29-23)21(14-19)18-6-8-25(2,3)9-7-18/h4-6,14,16,34H,7-13H2,1-3H3,(H,28,29)(H,30,33)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.700n/an/an/an/a7.525



Janssen Pharmaceutica NV

US Patent


Assay Description
An autophosphorylation, fluorescence polarization competition immunoassay was used to determine the potency for c-fms inhibition exhibited by selecte...


US Patent US9394289 (2016)


BindingDB Entry DOI: 10.7270/Q28K780X
More data for this
Ligand-Target Pair