Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM238142'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (Mus musculus (Mouse))	BDBM238142 (US9394289, 90) Show SMILES CC1(C)CCC(=CC1)c1cc(ccc1NC(=O)c1nc(c[nH]1)C#N)C1(O)CCN(CC(F)(F)F)CC1 |c:5| Show InChI InChI=1S/C26H30F3N5O2/c1-24(2)7-5-17(6-8-24)20-13-18(25(36)9-11-34(12-10-25)16-26(27,28)29)3-4-21(20)33-23(35)22-31-15-19(14-30)32-22/h3-5,13,15,36H,6-12,16H2,1-2H3,(H,31,32)(H,33,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.5	n/a	n/a	n/a	n/a	7.5	25
Janssen Pharmaceutica NV US Patent					Assay Description An autophosphorylation, fluorescence polarization competition immunoassay was used to determine the potency for c-fms inhibition exhibited by selecte...				US Patent US9394289 (2016) BindingDB Entry DOI: 10.7270/Q28K780X
					More data for this Ligand-Target Pair