BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM27632'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM27632
PNG
(N-{3-[(1S)-1-[(6-chloropyrazin-2-yl)amino]ethyl]ph...)
Show SMILES C[C@H](Nc1cncc(Cl)n1)c1cccc(NC(=O)c2ccc(C)cc2)c1 |r|
Show InChI InChI=1S/C20H19ClN4O/c1-13-6-8-15(9-7-13)20(26)24-17-5-3-4-16(10-17)14(2)23-19-12-22-11-18(21)25-19/h3-12,14H,1-2H3,(H,23,25)(H,24,26)/t14-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 9n/an/an/an/a7.537



Cytopia Research Pty Ltd



Assay Description
Kinase assays were performed in 384 well Optiplates (Packard) using an Alphascreen Protein Tyrosine Kinase kit. Inhibitors were added to the mixtures...


Bioorg Med Chem Lett 19: 1206-9 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.073
BindingDB Entry DOI: 10.7270/Q2PZ5742
More data for this
Ligand-Target Pair