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Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM50312743'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))		BDBM50312743
PNG
(3-(5-methoxy-6-(4-methoxybenzyloxy)pyridin-3-yloxy...)
Show SMILES COc1ccc(COc2ncc(Oc3nc(cnc3N)-c3cnn(C)c3)cc2OC)cc1
Show InChI InChI=1S/C22H22N6O4/c1-28-12-15(9-26-28)18-11-24-20(23)22(27-18)32-17-8-19(30-3)21(25-10-17)31-13-14-4-6-16(29-2)7-5-14/h4-12H,13H2,1-3H3,(H2,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Pfizer Global Research& Development

Curated by ChEMBL


Assay Description
Inhibition of human CSF1R autophosphorylation expressed in HEK293 cells after 1 hr by ELISA

Bioorg Med Chem Lett 20: 1543-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.078
BindingDB Entry DOI: 10.7270/Q2513Z98
More data for this
Ligand-Target Pair