Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM50443159'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (Mus musculus (Mouse))	BDBM50443159 (CHEMBL3085834 | US8674100, 77) Show SMILES COCCN1CCN(CC1)C(C)(C)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:32| Show InChI InChI=1S/C29H40N6O2/c1-28(2)10-8-21(9-11-28)24-18-22(29(3,4)35-14-12-34(13-15-35)16-17-37-5)6-7-25(24)33-27(36)26-31-20-23(19-30)32-26/h6-8,18,20H,9-17H2,1-5H3,(H,31,32)(H,33,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica, N.V. US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...				US Patent US8674100 (2014) BindingDB Entry DOI: 10.7270/Q23777CF
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM50443159 (CHEMBL3085834 | US8674100, 77) Show SMILES COCCN1CCN(CC1)C(C)(C)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:32| Show InChI InChI=1S/C29H40N6O2/c1-28(2)10-8-21(9-11-28)24-18-22(29(3,4)35-14-12-34(13-15-35)16-17-37-5)6-7-25(24)33-27(36)26-31-20-23(19-30)32-26/h6-8,18,20H,9-17H2,1-5H3,(H,31,32)(H,33,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of FMS (unknown origin)				Bioorg Med Chem Lett 23: 6363-9 (2013) Article DOI: 10.1016/j.bmcl.2013.09.061 BindingDB Entry DOI: 10.7270/Q2MP54RH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Mus musculus (Mouse))	BDBM50443159 (CHEMBL3085834 | US8674100, 77) Show SMILES COCCN1CCN(CC1)C(C)(C)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:32| Show InChI InChI=1S/C29H40N6O2/c1-28(2)10-8-21(9-11-28)24-18-22(29(3,4)35-14-12-34(13-15-35)16-17-37-5)6-7-25(24)33-27(36)26-31-20-23(19-30)32-26/h6-8,18,20H,9-17H2,1-5H3,(H,31,32)(H,33,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of FMS in mouse BMDM cells				Bioorg Med Chem Lett 23: 6363-9 (2013) Article DOI: 10.1016/j.bmcl.2013.09.061 BindingDB Entry DOI: 10.7270/Q2MP54RH
					More data for this Ligand-Target Pair