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Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM50518399'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))		BDBM50518399
PNG
(CHEMBL4552261)
Show SMILES Cc1cccc(Cn2nc(I)c3c(NC(=O)c4csc5c(N)ncnc45)cccc23)n1
Show InChI InChI=1S/C21H16IN7OS/c1-11-4-2-5-12(26-11)8-29-15-7-3-6-14(16(15)19(22)28-29)27-21(30)13-9-31-18-17(13)24-10-25-20(18)23/h2-7,9-10H,8H2,1H3,(H,27,30)(H2,23,24,25)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9n/an/an/an/an/an/a



Chung-Ang University

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...

Bioorg Med Chem Lett 29: 271-275 (2019)


Article DOI: 10.1016/j.bmcl.2018.11.037
BindingDB Entry DOI: 10.7270/Q2QJ7MN8
More data for this
Ligand-Target Pair