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Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM50518401'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))		BDBM50518401
PNG
(CHEMBL4438472)
Show SMILES Nc1ncnc2c(csc12)C(=O)Nc1cccc2n(Cc3cccc(F)n3)nc(Br)c12
Show InChI InChI=1S/C20H13BrFN7OS/c21-18-15-12(27-20(30)11-8-31-17-16(11)24-9-25-19(17)23)4-2-5-13(15)29(28-18)7-10-3-1-6-14(22)26-10/h1-6,8-9H,7H2,(H,27,30)(H2,23,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Chung-Ang University

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...

Bioorg Med Chem Lett 29: 271-275 (2019)


Article DOI: 10.1016/j.bmcl.2018.11.037
BindingDB Entry DOI: 10.7270/Q2QJ7MN8
More data for this
Ligand-Target Pair