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Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM50518405'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))		BDBM50518405
PNG
(CHEMBL4462286)
Show SMILES Nc1ncnc2c(csc12)C(=O)Nc1cccc2n(Cc3ccncc3)nc(Br)c12
Show InChI InChI=1S/C20H14BrN7OS/c21-18-15-13(26-20(29)12-9-30-17-16(12)24-10-25-19(17)22)2-1-3-14(15)28(27-18)8-11-4-6-23-7-5-11/h1-7,9-10H,8H2,(H,26,29)(H2,22,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Chung-Ang University

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...

Bioorg Med Chem Lett 29: 271-275 (2019)


Article DOI: 10.1016/j.bmcl.2018.11.037
BindingDB Entry DOI: 10.7270/Q2QJ7MN8
More data for this
Ligand-Target Pair