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Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM50518415'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))		BDBM50518415
PNG
(CHEMBL4436822)
Show SMILES CCc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3csc4c(N)ncnc34)c12
Show InChI InChI=1S/C23H21N7OS/c1-3-16-19-17(28-23(31)15-11-32-21-20(15)25-12-26-22(21)24)8-5-9-18(19)30(29-16)10-14-7-4-6-13(2)27-14/h4-9,11-12H,3,10H2,1-2H3,(H,28,31)(H2,24,25,26)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9n/an/an/an/an/an/a



Chung-Ang University

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human N-terminal His6-tagged FMS (538 to end residues) expressed in baculovirus infected Sf21 insect cells using I...

Bioorg Med Chem Lett 29: 271-275 (2019)


Article DOI: 10.1016/j.bmcl.2018.11.037
BindingDB Entry DOI: 10.7270/Q2QJ7MN8
More data for this
Ligand-Target Pair