BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM98620'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Mus musculus (Mouse))
BDBM98620
PNG
(US8497376, 1)
Show SMILES COC[C@@]12C[C@](O)(C[C@@](COC)(O1)C=C2)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |r,c:14,t:35|
Show InChI InChI=1S/C30H36N4O5/c1-27(2)9-7-20(8-10-27)23-13-21(5-6-24(23)34-26(35)25-32-15-22(14-31)33-25)30(36)16-28(18-37-3)11-12-29(17-30,39-28)19-38-4/h5-7,11-13,15,36H,8-10,16-19H2,1-4H3,(H,32,33)(H,34,35)/t28-,29+,30+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 0.860n/an/an/an/a7.5n/a



Janssen Pharmaceutica N.V.

US Patent


Assay Description
An autophosphorylation, fluroescence polarization competition immunoassay was used to determine the potency for c-fms inhibition.


US Patent US8497376 (2013)


BindingDB Entry DOI: 10.7270/Q2RN36GW
More data for this
Ligand-Target Pair