Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM98630'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (Mus musculus (Mouse))	BDBM98630 (US8497376, 11) Show SMILES CC1(C)O[C@H]2[C@@H](O1)[C@]1(C)C[C@](O)(C[C@@]2(C)O1)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |r,t:37| Show InChI InChI=1S/C31H38N4O5/c1-27(2)11-9-18(10-12-27)21-13-19(7-8-22(21)35-26(36)25-33-15-20(14-32)34-25)31(37)16-29(5)23-24(30(6,17-31)40-29)39-28(3,4)38-23/h7-9,13,15,23-24,37H,10-12,16-17H2,1-6H3,(H,33,34)(H,35,36)/t23-,24+,29+,30-,31+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica N.V. US Patent					Assay Description An autophosphorylation, fluroescence polarization competition immunoassay was used to determine the potency for c-fms inhibition.				US Patent US8497376 (2013) BindingDB Entry DOI: 10.7270/Q2RN36GW
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