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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM98632'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Mus musculus (Mouse))
BDBM98632
PNG
(US8497376, 13)
Show SMILES C[C@@]12C[C@@H](C[C@@](C)(O1)[C@@H](O)[C@H]2O)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |r,t:32|
Show InChI InChI=1S/C28H34N4O4/c1-26(2)9-7-16(8-10-26)20-11-17(18-12-27(3)22(33)23(34)28(4,13-18)36-27)5-6-21(20)32-25(35)24-30-15-19(14-29)31-24/h5-7,11,15,18,22-23,33-34H,8-10,12-13H2,1-4H3,(H,30,31)(H,32,35)/t18-,22+,23-,27-,28+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 0.810n/an/an/an/a7.5n/a



Janssen Pharmaceutica N.V.

US Patent


Assay Description
An autophosphorylation, fluroescence polarization competition immunoassay was used to determine the potency for c-fms inhibition.


US Patent US8497376 (2013)


BindingDB Entry DOI: 10.7270/Q2RN36GW
More data for this
Ligand-Target Pair