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Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM98647'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Mus musculus (Mouse))
BDBM98647
PNG
(US8497376, 26)
Show SMILES CC1(C)CCC(=CC1)c1cc(ccc1NC(=O)c1ncc([nH]1)C#N)C1=C[C@H]2O[C@@H](C1)C=C2 |r,c:5,34,t:27|
Show InChI InChI=1S/C26H26N4O2/c1-26(2)9-7-16(8-10-26)22-13-17(18-11-20-4-5-21(12-18)32-20)3-6-23(22)30-25(31)24-28-15-19(14-27)29-24/h3-7,11,13,15,20-21H,8-10,12H2,1-2H3,(H,28,29)(H,30,31)/t20-,21+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 7.10n/an/an/an/a7.5n/a



Janssen Pharmaceutica N.V.

US Patent


Assay Description
An autophosphorylation, fluroescence polarization competition immunoassay was used to determine the potency for c-fms inhibition.


US Patent US8497376 (2013)


BindingDB Entry DOI: 10.7270/Q2RN36GW
More data for this
Ligand-Target Pair