Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor [555-568]' and Ligand = 'BDBM119033'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor [555-568] (Homo sapiens (Human))	BDBM119033 (US8674100, 46 | US9221797, 46) Show SMILES CC1(C)CCC(=CC1)c1cc(ccc1NC(=O)c1ncc([nH]1)C#N)C(O)C(O)=O |c:5| Show InChI InChI=1S/C21H22N4O4/c1-21(2)7-5-12(6-8-21)15-9-13(17(26)20(28)29)3-4-16(15)25-19(27)18-23-11-14(10-22)24-18/h3-5,9,11,17,26H,6-8H2,1-2H3,(H,23,24)(H,25,27)(H,28,29)	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica NV US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...				US Patent US9221797 (2015) BindingDB Entry DOI: 10.7270/Q2W37V4H
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