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Found 1 hit Enz. Inhib. hit(s) with Target = 'Malate dehydrogenase, mitochondrial' and Ligand = 'BDBM50522576'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Malate dehydrogenase, mitochondrial


(Sus scrofa (pig))		BDBM50522576
PNG
(CHEMBL4567660)
Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1ccc(cc1)-c1nc2ccccc2o1
Show InChI InChI=1S/C20H15ClN2O4S/c1-26-18-11-8-14(21)12-19(18)28(24,25)23-15-9-6-13(7-10-15)20-22-16-4-2-3-5-17(16)27-20/h2-12,23H,1H3
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>6.30E+4n/an/an/an/an/an/a



Indiana University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of refolded pig heart mitochondrial MDH preincubated with Escherichia coli GroEL/GroES for 45 mins using sodium mesoxalate as substrate fo...

Bioorg Med Chem Lett 29: 1665-1672 (2019)


Article DOI: 10.1016/j.bmcl.2019.04.034
BindingDB Entry DOI: 10.7270/Q2MG7SWV
More data for this
Ligand-Target Pair