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Found 1 hit Enz. Inhib. hit(s) with Target = 'Malate dehydrogenase, mitochondrial' and Ligand = 'BDBM50522581'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Malate dehydrogenase, mitochondrial


(Sus scrofa (pig))		BDBM50522581
PNG
(CHEMBL4556062)
Show SMILES [O-][N+](=O)c1cc(ccc1Cl)S(=O)(=O)Nc1ccc2oc(nc2c1)-c1ccccc1
Show InChI InChI=1S/C19H12ClN3O5S/c20-15-8-7-14(11-17(15)23(24)25)29(26,27)22-13-6-9-18-16(10-13)21-19(28-18)12-4-2-1-3-5-12/h1-11,22H
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>6.30E+4n/an/an/an/an/an/a



Indiana University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of refolded pig heart mitochondrial MDH preincubated with Escherichia coli GroEL/GroES for 45 mins using sodium mesoxalate as substrate fo...

Bioorg Med Chem Lett 29: 1665-1672 (2019)


Article DOI: 10.1016/j.bmcl.2019.04.034
BindingDB Entry DOI: 10.7270/Q2MG7SWV
More data for this
Ligand-Target Pair