Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mannose-6-phosphate isomerase (Homo sapiens (Human)) | BDBM34737 (2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one | ...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Inhibition of phosphomannose isomerase (unknown origin) | Bioorg Med Chem Lett 24: 4308-11 (2014) Article DOI: 10.1016/j.bmcl.2014.07.013 BindingDB Entry DOI: 10.7270/Q2GX4D7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mannose-6-phosphate isomerase (Homo sapiens (Human)) | BDBM34737 (2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one | ...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | 4.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2J964TC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mannose-6-phosphate isomerase (Homo sapiens (Human)) | BDBM34737 (2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one | ...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Inhibition of human purified phosphomannose isomerase | J Med Chem 54: 3661-8 (2011) Article DOI: 10.1021/jm101401a BindingDB Entry DOI: 10.7270/Q28C9WKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mannose-6-phosphate isomerase (Homo sapiens (Human)) | BDBM34737 (2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one | ...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | 6.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2C827QV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mannose-6-phosphate isomerase (Homo sapiens (Human)) | BDBM34737 (2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one | ...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | 7.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2J964TC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mannose-6-phosphate isomerase (Homo sapiens (Human)) | BDBM34737 (2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one | ...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2CF9NFM | |||||||||||
More data for this Ligand-Target Pair |