Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit [D816V]' and Ligand = 'BDBM175443'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit [D816V] (Homo sapiens (Human))	BDBM175443 (US9688680, 43) Show SMILES CC(C)n1cc(cn1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)Nc1ccc(cc1)C#N Show InChI InChI=1S/C23H22N8O/c1-15(2)30-13-18(9-26-30)17-7-21-22(25-14-27-31(21)12-17)29-10-19(11-29)23(32)28-20-5-3-16(8-24)4-6-20/h3-7,9,12-15,19H,10-11H2,1-2H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.5	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description In each well of a 384-well plate, 0.2 ng/ul final (2 nM) of wild type Kit (Carna Bioscience 08-156) was incubated in a total of 12.5 ul of buffer (10...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
					More data for this Ligand-Target Pair