Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit [D816V]' and Ligand = 'BDBM342180'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit [D816V] (Homo sapiens (Human))	BDBM342180 (4-[4-[5-(3-fluorophenyl)-4-methyl-1H- imidazol-2-y...) Show SMILES COc1cc(ccn1)-c1cc2c(ncnc2[nH]1)N1CCC(CC1)c1nc(C)c([nH]1)-c1cccc(F)c1 Show InChI InChI=1S/C27H26FN7O/c1-16-24(19-4-3-5-20(28)12-19)34-25(32-16)17-7-10-35(11-8-17)27-21-14-22(33-26(21)30-15-31-27)18-6-9-29-23(13-18)36-2/h3-6,9,12-15,17H,7-8,10-11H2,1-2H3,(H,32,34)(H,30,31,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...				US Patent US9771369 (2017) BindingDB Entry DOI: 10.7270/Q24J0H7Q
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