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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit [D816V]' and Ligand = 'BDBM342234'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mast/stem cell growth factor receptor Kit [D816V]


(Homo sapiens (Human))		BDBM342234
PNG
(4-[4-[4-[5-(4-ethoxy-3-methyl-phenyl)- 4-methyl-1H...)
Show SMILES CCOc1ccc(cc1C)-c1[nH]c(nc1C)C1CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(cc1)C#N
Show InChI InChI=1S/C31H31N7O/c1-4-39-27-10-9-24(15-19(27)2)28-20(3)35-29(37-28)23-11-13-38(14-12-23)31-25-16-26(36-30(25)33-18-34-31)22-7-5-21(17-32)6-8-22/h5-10,15-16,18,23H,4,11-14H2,1-3H3,(H,35,37)(H,33,34,36)
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
 500n/an/an/an/an/an/an/an/a



Plexxikon Inc.

US Patent


Assay Description
The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...

US Patent US9771369 (2017)


BindingDB Entry DOI: 10.7270/Q24J0H7Q
More data for this
Ligand-Target Pair