Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit [V560G,D816V]' and Ligand = 'BDBM175620'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175620 (US9688680, 169) Show SMILES CCC(C)(O)c1ccc(cc1)-c1cc2c(ncnn2c1)N1CC(C1)C(=O)NCc1ccc(C)cc1 Show InChI InChI=1S/C28H31N5O2/c1-4-28(3,35)24-11-9-21(10-12-24)22-13-25-26(30-18-31-33(25)17-22)32-15-23(16-32)27(34)29-14-20-7-5-19(2)6-8-20/h5-13,17-18,23,35H,4,14-16H2,1-3H3,(H,29,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
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